Facilitating Clinical Implementation of Pharmacogenomics

Perspective of Clinical Nurses on Facilitating Factors and Obstacles of Conducting Research and Implementation of Its Results

Background: Participation of nurses in research studies is a requirement of achieving evidence-based nursing, but studies in this regard are limited. This study aimed to determine the viewpoints of nurses regarding the facilitating factors and obstacles of participating in research and utilization of its results in clinical practice. Methods: This descriptive study was done in 2013 at teaching ...

CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network.

Incorporation of Pharmacogenomics into Routine Clinical Practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline Development Process

The Clinical Pharmacogenetics Implementation Consortium (CPIC) publishes genotype-based drug guidelines to help clinicians understand how available genetic test results could be used to optimize drug therapy. CPIC has focused initially on well-known examples of pharmacogenomic associations that have been implemented in selected clinical settings, publishing nine to date. Each CPIC guideline adh...

Supporting implementation through collaborative learning: facilitating access to clinical expertise

Objective Learning collaboratives (LCs) have potential to promote implementation of empirically supported treatments (ESTs) in healthcare organizations and systems by building networks among clinicians and with key content experts that facilitate shared expertise. However, the effectiveness of LCs for facilitating clinicians’ access to expertise, and implementation success is untested. This stu...

Pharmacogenomics in Clinical Practice

The Promise of Pharmacogenomics As genomic medicine advances, there is hope that genetic biomarkers will encourage movement away from empirical and population-based treatment approaches to those that are stratified according to better patient outcomes, thus ending a “trial-and-error” approach to therapy.4,6–8 It is estimated that only 50% of patients respond positively to their medications.5,9 ...